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KMID : 0361019950380040544
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Korean Journal of Otolaryngology - Head and Neck Surgery
1995 Volume.38 No. 4 p.544 ~ p.548
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Immunohistochemical and Electron Microscopic Studies of Substance P Innevation in Guinea Pig Nasal Glands
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전시영
김진평/안성기/황의기/훙순관
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Abstract
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The distribution of substance P immunoreactive (SP-IR) nerve endings in the nasal gland of the guinea pig was studies by immunohistochemical elecron microscopy using avidin-biotin-peroxidase complex (ABC) method and pre-embedding technique. The
SP-IR
nerve endings were located in the region between the interdigitated cytoplasmic folds of the acinar cells and along the basal surface of the acini, as well as in the intercellular space of proximal ducts. The acini which closely contacted with
SP-IR
nerve endings were serous in type. These findings suggest that substance P may contribute to the regulation of serous glandular secretion in the guinea pig nasal mucosa. (Korean J Otolaryngol 38:4, 1995)
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KEYWORD
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